Despite a strong defensive performance, Southern Miss (2-6, 1-3 Conference USA) fell short of completing a fourth-quarter comeback against Western Kentucky (3-6, 2-3 Conference USA) and lost 10-7.

After starting this season by losing four home games, Southern Miss (2-5, 1-2 Conference USA) earned its first win at home since 2019 with a 24-13 victory against North Alabama.